Annunciation is a painting by the Italian Renaissance artists Leonardo da Vinci.The subject matter is drawn from Luke and depicts the angel Gabriel, sent by God to announce to a virgin, Mary, that she would miraculously conceive and give birth to a son, to be named Jesus, and to be called "the Son of God" whose reign would never end. The subject was very popular for artworks and had been depicted many times in the art of Florence, including several examples by the Early Renaissance painter Fra Angelico.